External Globus Pallidus Stimulation Modulates Brain Connectivity in Huntington's Disease

Positron emission tomography with O-15-labeled water was used to study at rest the neurophysiological effects of bilateral external globus pallidus (GPe) deep brain stimulation in patients with Huntington's disease (HD). Five patients were compared with a control group in the on and off states...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2011-01, Vol.31 (1), p.41-46
Hauptverfasser:	Ligot, Noémie, Krystkowiak, Pierre, Simonin, Clémence, Goldman, Serge, Peigneux, Philippe, Van Naemen, John, Monclus, Michel, Lacroix, Simon Frédéric, Devos, David, Dujardin, Kathy, Delmaire, Christine, Bardinet, Eric, Delval, Arnaud, Delliaux, Marie, Defebvre, Luc, Yelnik, Jerome, Blond, Serge, Destée, Alain, De Tiège, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Basal Ganglia - physiology Biological and medical sciences Brief Communication Cerebral Cortex - physiology Cerebrovascular Circulation - physiology Computer Science Deep Brain Stimulation Female Globus Pallidus - physiology Humans Huntington Disease - diagnostic imaging Huntington Disease - therapy Image Processing, Computer-Assisted Investigative techniques, diagnostic techniques (general aspects) Male Medical Imaging Medical sciences Middle Aged Nerve Net - physiology Nervous system Neural Pathways - physiology Neurology Neurons - physiology Oxygen Radioisotopes Positron-Emission Tomography Thalamus - physiology Ultrasonic investigative techniques Vascular diseases and vascular malformations of the nervous system
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