NADPH-dependent Reductases Involved in the Detoxification of Reactive Carbonyls in Plants

Reactive carbonyls, especially α,β-unsaturated carbonyls produced through lipid peroxidation, damage biomolecules such as proteins and nucleotides; elimination of these carbonyls is therefore essential for maintaining cellular homeostasis. In this study, we focused on an NADPH-dependent detoxificati...

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Veröffentlicht in:	The Journal of biological chemistry 2011-03, Vol.286 (9), p.6999-7009
Hauptverfasser:	Yamauchi, Yasuo, Hasegawa, Ayaka, Taninaka, Ai, Mizutani, Masaharu, Sugimoto, Yukihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrolein - metabolism Alcohol Oxidoreductases - genetics Alcohol Oxidoreductases - metabolism Aldehyde Reductase - genetics Aldehyde Reductase - metabolism Aldehydes - metabolism Aldo-Keto Reductases Arabidopsis Arabidopsis - enzymology Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism Chloroplast Chloroplasts - enzymology Cucumber Cucumis sativus - enzymology Enzyme Purification Lipid Peroxidation Lipid Peroxidation - physiology Molecular Sequence Data NADP - metabolism Oxidative Stress Oxidoreductases - genetics Oxidoreductases - metabolism Plant Biology Pyruvaldehyde - metabolism Reactive Carbonyls Reactive Oxygen Species Reductase Substrate Specificity
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