Mitotic Recombination between Homologous Chromosomes Generates H-2 Somatic Cell Variants in vitro

A spontaneously arising variant clone that does not express the H-2Ddand H-2Ldmolecules was isolated by immunoselection from an (H-2b× H-2d)F1cell line. This variant clone expresses H-2Kb, H-2Db, and H-2Kdmolecules. Southern blot analysis demonstrated that the variant was heterozygous at the H-2K, I...

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