Developmental control of the Nlrp6 inflammasome and a substrate, IL-18, in mammalian intestine

The inflammasome is a multiprotein complex whose formation is triggered when a NOD-like receptor binds a pathogen ligand, resulting in activated caspase-1, which converts certain interleukins (IL-1β, IL-18, and IL-33) to their active forms. There is currently no information on regulation of this sys...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2011-02, Vol.300 (2), p.G253-G263
Hauptverfasser:	Kempster, Sarah L, Belteki, Gusztav, Forhead, Alison J, Fowden, Abigail L, Catalano, Robert D, Lam, Brian Y, McFarlane, Ian, Charnock-Jones, D Stephen, Smith, Gordon C S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Binding Sites Cell Line, Tumor Cytokines Digestive system Embryo, Mammalian - metabolism Embryonic Development Gene Expression Profiling - methods Gene Expression Regulation Gestational Age Humans Immunity, Innate - genetics Immunohistochemistry Inflammasomes - genetics Inflammasomes - metabolism Inflammation/Immunity/Mediators Interleukin-8 - metabolism Intestinal Mucosa - embryology Intestines - embryology Lung - embryology Microarray Analysis Physiology PPAR gamma - metabolism Proteins Rats - embryology Rats, Wistar Receptors, Angiotensin - genetics Receptors, Angiotensin - metabolism Receptors, Vasopressin - genetics Receptors, Vasopressin - metabolism Reproducibility of Results Reverse Transcriptase Polymerase Chain Reaction - methods Ribonucleic acid RNA RNA, Messenger - metabolism Rodents Sheep - embryology Transcription Factors - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!