Inflammatory signals regulate hematopoietic stem cells

Hematopoietic stem cells (HSCs) are the progenitors of all blood and immune cells, yet their role in immunity is not well understood. Most studies have focused on the ability of committed lymphoid and myeloid precursors to replenish immune cells during infection. Recent studies, however, have indica...

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Veröffentlicht in:	Trends in immunology 2011-02, Vol.32 (2), p.57-65
Hauptverfasser:	Baldridge, Megan T, King, Katherine Y, Goodell, Margaret A
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Apoptosis Blood Bone marrow Cell Proliferation Cytokines Cytokines - immunology Cytomegalovirus Disseminated infection E coli Effector cells Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Hemopoiesis Humans Immune system Immunity Infections Inflammation Inflammation - immunology Interferon interferons Listeria necrosis Population receptors Reviews Rodents Sepsis Signal Transduction Stem cells Studies Toll-like receptors Toll-Like Receptors - immunology Transplants & implants Tumor necrosis factor- alpha Viral infections
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