Neural tube defects in mice exposed to tap water

In May of 2006 we suddenly began to observe neural tube defects (NTDs) in embryos of untreated control mice. We hypothesized the mice were being exposed unknowingly to a teratogenic agent and investigated the cause. Our results suggested that NTDs were not resulting from bedding material, feed, stra...

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Veröffentlicht in:	Environmental toxicology 2011-11, Vol.26 (6), p.633-640
Hauptverfasser:	Mallela, Murali K., Werre, Stephen R., Hrubec, Terry C.
Format:	Artikel
Sprache:	eng
Schlagworte:	abnormal development adverse effects analysis Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences breeding chemically induced chemistry Drinking Water Drinking Water - adverse effects Drinking Water - analysis Drinking Water - chemistry drug effects Ecotoxicology, biological effects of pollution Female Fundamental and applied biological sciences. Psychology General aspects geographical distribution Male Mice Neural Tube Neural Tube - drug effects Neural Tube - pathology neural tube defects Neural Tube Defects - chemically induced neural tube defects tap water pathogens pathology pollutants Pregnancy Pregnancy Complications progeny purchasing tap water teratogenicity Teratogens Teratogens - analysis Teratogens - toxicity toxicity urban areas water analysis Water Pollutants, Chemical Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity
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