Novel sequence variations in LAMA2 andSGCG genes modulating cis-acting regulatory elements and RNA secondary structure

In this study, we detected new sequence variations in LAMA2 and SGCG genes in 5 ethnic populations, and analysed their effect on enhancer composition and mRNA structure. PCR amplification and DNA sequencing were performed and followed by bioinformatics analyses using ESEfinder as well as MFOLD softw...

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Veröffentlicht in:Genetics and molecular biology 2010-01, Vol.33 (1), p.190-197
Hauptverfasser: Siala, Olfa, Salem, Ikhlass Hadj, Tlili, Abdelaziz, Ammar, Imen, Belguith, Hanen, Fakhfakh, Faiza
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Sprache:eng
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