Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival

Nitric oxide (NO) is an intracellular messenger in several cell systems, but its contribution to embryonic stem cell (ESC) biology has not been characterized. Exposure of ESCs to low concentrations (2–20 μ M) of the NO donor diethylenetriamine NO adduct confers protection from apoptosis elicited by...

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Veröffentlicht in:	Cell death & disease 2010-10, Vol.1 (10), p.e80-e80
Hauptverfasser:	Tejedo, J R, Tapia-Limonchi, R, Mora-Castilla, S, Cahuana, G M, Hmadcha, A, Martin, F, Bedoya, F J, Soria, B
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/142 631/136/532/2117 631/136/532/2441 631/80/86 Animals Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell Differentiation Cell Survival Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Homeodomain Proteins - metabolism Humans Immunology Leukemia Inhibitory Factor - metabolism Lewis X Antigen - metabolism Life Sciences Mice Nitric Oxide - metabolism Nitric Oxide Synthase Type III - metabolism Octamer Transcription Factor-3 - metabolism Original original-article Polyamines - pharmacology SOXB1 Transcription Factors - metabolism
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