Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression

The adenovirus genome forms chromatin-like structure with viral core proteins. This complex supports only a low level of transcription in a cell-free system, and thus core proteins have been thought to be negative factors for transcription. The mechanism how the transcription from the viral DNA comp...

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Veröffentlicht in:	Nucleic acids research 2011-02, Vol.39 (3), p.889-901
Hauptverfasser:	Komatsu, Tetsuro, Haruki, Hirohito, Nagata, Kyosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Adenoviridae - genetics Adenoviridae - metabolism Adenovirus Cell-free system Chromatin Chromatin - metabolism Core protein DNA Gene expression Gene Expression Regulation, Viral Gene Regulation, Chromatin and Epigenetics Genomes HeLa Cells Histone Acetyltransferases Histone H3 Histones Histones - metabolism Humans Infection Plasmids Promoter Regions, Genetic Promoters TATA-Binding Protein Associated Factors - physiology Transcription Transcription Factor TFIID - physiology Transcription, Genetic Viral Core Proteins - metabolism
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