Mathematical and experimental approaches to identify and predict the effects of chemotherapy on neuroglial precursors

The adverse effects of chemotherapy on normal cells of the body create substantial clinical problems for many cancer patients. However, relatively little is known about the effects, other than promotion of cell death, of such agents on the function of normal precursor cells critical in tissue homeos...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2010-12, Vol.70 (24), p.10051-10059
Hauptverfasser:	Hyrien, Ollivier, Dietrich, Jörg, Noble, Mark
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Alkylating - pharmacology Brain - cytology Brain - drug effects Carmustine - pharmacology Cell Differentiation - drug effects Cell Growth Processes - drug effects Humans Models, Biological Neuroglia - cytology Neuroglia - drug effects Oligodendroglia - cytology Oligodendroglia - drug effects Stem Cells - cytology Stem Cells - drug effects
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