Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a dynamic nuclear and sarcomeric protein

Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a candidate gene for mediating FSHD pathophysiology, however, very little is known about the endogenous FRG1 protein. This study uses immunocytochemistry (ICC) and histology to provide insight into FRG1’s role in vertebrate muscle...

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Veröffentlicht in:	Differentiation (London) 2011-02, Vol.81 (2), p.107-118
Hauptverfasser:	Hanel, Meredith L., Sun, Chia-Yun Jessica, Jones, Takako I., Long, Steven W., Zanotti, Simona, Milner, Derek, Jones, Peter L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Cell Nucleus - metabolism Cells, Cultured Facioscapulohumeral muscular dystrophy FRG1 Gene Knockdown Techniques HeLa Cells Humans Mice Mice, Inbred C57BL Microfilament Proteins Muscle Muscle Fibers, Skeletal - metabolism Muscular Dystrophy, Facioscapulohumeral - genetics Muscular Dystrophy, Facioscapulohumeral - metabolism Myofibrils - metabolism Nuclear Proteins - genetics Nuclear Proteins - metabolism RNA-Binding Proteins Sarcomere Sarcomeres - metabolism Z-disc
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