Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2g2

Ube2g2 is a human ubiquitin conjugating (E2) enzyme involved in the endoplasmic reticulum-associated degradation pathway, which is responsible for the identification and degradation of unfolded and misfolded proteins in the endoplasmic reticulum compartment. The Ube2g2-specific role is the assembly...

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Veröffentlicht in:	The Journal of biological chemistry 2011-02, Vol.286 (5), p.3981-3991
Hauptverfasser:	Bocik, William E., Sircar, Aroop, Gray, Jeffrey J., Tolman, Joel R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysics Enzyme Processing Humans Lysine Magnetic Resonance Spectroscopy Models, Molecular Molecular Biophysics NMR Polyubiquitin - metabolism Protein Binding Ubiquitin Ubiquitin - metabolism Ubiquitin Conjugating Enzyme (Ubc) Ubiquitin-Conjugating Enzymes - metabolism Ubiquitination
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