Molecular Dynamics Studies of Ion Permeation in VDAC

The voltage-dependent anion channel (VDAC) in the outer membrane of mitochondria serves an essential role in the transport of metabolites and electrolytes between the cell matrix and mitochondria. To examine its structure, dynamics, and the mechanisms underlying its electrophysiological properties,...

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Veröffentlicht in:	Biophysical journal 2011-02, Vol.100 (3), p.602-610
Hauptverfasser:	Rui, Huan, Lee, Kyu Il, Pastor, Richard W., Im, Wonpil
Format:	Artikel
Sprache:	eng
Schlagworte:	Anions Channels Channels and Transporters Density distribution Diffusion Electric currents Electrolytes Electrophysiological Phenomena Humans Ions Ions - metabolism Lipid Bilayers - metabolism Magnetic Resonance Spectroscopy Measurement Membranes metabolites Mitochondria mitochondrial membrane Molecular dynamics Molecular Dynamics Simulation Molecular structure Permeability Porosity potassium potassium chloride Selectivity Simulation Static Electricity Voltage-Dependent Anion Channel 1 - chemistry Voltage-Dependent Anion Channel 1 - metabolism Walls
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