Mechanisms of cerebrovascular protection: oestrogen, inflammation and mitochondria

Investigation of oestrogen action reveals a multitude of diverse effects. This brief review focuses on the impact of oestrogen on the vasculature, with particular emphasis on the cerebral circulation. Three major actions of oestrogen are discussed: enhancement of vasodilator capacity, suppression of...

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Veröffentlicht in:	Acta Physiologica 2011-09, Vol.203 (1), p.149-154
Hauptverfasser:	Duckles, S. P., Krause, D. N.
Format:	Artikel
Sprache:	eng
Schlagworte:	17 beta -Estradiol AKT protein Animals Biological and medical sciences Blood vessels Cerebral blood flow Cerebrovascular Circulation - drug effects Cerebrovascular Circulation - physiology Electron transfer Endothelium Estrogen receptors Estrogens - metabolism Estrogens - pharmacology Estrus cycle Female Fundamental and applied biological sciences. Psychology gonadal steroids Humans Inflammation Inflammation - metabolism Life span Manganese Mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitochondrial DNA Nitric-oxide synthase Phosphorylation Reviews Superoxide dismutase Transcription factors vascular inflammation vascular protection Vasodilators Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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