Exploring the limits of ultrafast polymerase chain reaction using liquid for thermal heat exchange: A proof of principle

Thermal ramp rate is a major limiting factor in using real-time polymerase chain reaction (PCR) for routine diagnostics. We explored the limits of speed by using liquid for thermal exchange rather than metal as in traditional devices, and by testing different polymerases. In a clinical setting, our...

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Veröffentlicht in:	Applied physics letters 2010-12, Vol.97 (26), p.264101-264101
Hauptverfasser:	Maltezos, George, Johnston, Matthew, Taganov, Konstantin, Srichantaratsamee, Chutatip, Gorman, John, Baltimore, David, Chantratita, Wasun, Scherer, Axel
Format:	Artikel
Sprache:	eng
Schlagworte:	Interdisciplinary and General Physics
Online-Zugang:	Volltext
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