LTQ-iQuant: A freely available software pipeline for automated and accurate protein quantification of isobaric tagged peptide data from LTQ instruments

Pulsed Q dissociation enables combining LTQ ion trap instruments with isobaric peptide tagging. Unfortunately, this combination lacks a technique which accurately reports protein abundance ratios and is implemented in a freely available, flexible software pipeline. We developed and implemented a tec...

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Veröffentlicht in:	Proteomics (Weinheim) 2010-10, Vol.10 (19), p.3533-3538
Hauptverfasser:	Onsongo, Getiria, Stone, Matthew D, Van Riper, Susan K, Chilton, John, Wu, Baolin, Higgins, LeeAnn, Lund, Troy C, Carlis, John V, Griffin, Timothy J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Bioinformatics Biological and medical sciences Fundamental and applied biological sciences. Psychology Isobaric tags LTQ Miscellaneous Open source software Peptides - analysis Protein quantification Proteins Proteins - analysis Proteomics - methods Software Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Weighted average
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