Cerebral Perfusion and Aortic Stiffness Are Independent Predictors of White Matter Brain Atrophy in Type 1 Diabetic Patients Assessed With Magnetic Resonance Imaging

OBJECTIVE: To identify vascular mechanisms of brain atrophy in type 1 diabetes mellitus (DM) patients by investigating the relationship between brain volumes and cerebral perfusion and aortic stiffness using magnetic resonance imaging (MRI). RESEARCH DESIGN AND METHODS: Approval from the local insti...

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Veröffentlicht in:	Diabetes care 2011-02, Vol.34 (2), p.459-463
Hauptverfasser:	van Elderen, Saskia G.C, Brandts, Anne, van der Grond, Jeroen, Westenberg, Jos J.M, Kroft, Lucia J.M, van Buchem, Mark A, Smit, Johannes W.A, de Roos, Albert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aortic Diseases - pathology Atrophy Biological and medical sciences Brain Brain Diseases - pathology Brain Diseases - physiopathology Care and treatment Cerebrovascular Circulation - physiology Diabetes Diabetes Mellitus, Type 1 - pathology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - pathology Diabetic Angiopathies - physiopathology Diabetics Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Heart rate Humans Hypertension Leukoencephalopathies - pathology Leukoencephalopathies - physiopathology Magnetic Resonance Imaging Male Medical research Medical sciences Medicine, Experimental Metabolic diseases Middle Aged Miscellaneous Original Research Predictive Value of Tests Public health. Hygiene Public health. Hygiene-occupational medicine Severity of Illness Index Software packages Studies Type 1 diabetes Veins & arteries
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