Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation

The emerging discoveries on the link between polyadenylation and disease states underline the need to fully characterize genome-wide polyadenylation states. Here, we report comprehensive maps of global polyadenylation events in human and yeast generated using refinements to the Direct RNA Sequencing...

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Veröffentlicht in:	Cell 2010-12, Vol.143 (6), p.1018-1029
Hauptverfasser:	Ozsolak, Fatih, Kapranov, Philipp, Foissac, Sylvain, Kim, Sang Woo, Fishilevich, Elane, Monaghan, A. Paula, John, Bino, Milos, Patrice M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Profiling Humans Life Sciences Liver - metabolism Poly A - analysis Polyadenylation Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Sequence Analysis, RNA - methods
Online-Zugang:	Volltext
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