Toll-Like Receptor 2 Mediates Proliferation, Survival, NF-κB Translocation, and Cytokine mRNA Expression in LIF-Maintained Mouse Embryonic Stem Cells

Toll-like receptor (TLR) activation is important in immune responses and in differentiation of hematopoietic stem cells. We detected mRNA expression of TLRs 1, 2, 3, 5, and 6, but not TLRs 4, 7, 8, and 9 in murine (m)ESC line E14, and noted high cell surface protein expression of TLR2, but not TLR4,...

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Veröffentlicht in:	Stem cells and development 2010-09, Vol.19 (9), p.1333-1341
Hauptverfasser:	Taylor, Tammi, Kim, Young-June, Ou, Xuan, Derbigny, Wilbert, Broxmeyer, Hal E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell receptors Embryonic stem cells Immune response Original Research Reports Physiological aspects Translocation (Genetics)
Online-Zugang:	Volltext
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