Recruitment Timing and Dynamics of Transcription Factors at the Hsp70 Loci in Living Cells

Chromatin immunoprecipitation (ChIP) studies provide snapshots of factors on chromatin in cell populations. Here, we use live-cell imaging to examine at high temporal resolution the recruitment and dynamics of transcription factors to the inducible Hsp70 loci in individual Drosophila salivary gland...

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Veröffentlicht in:	Molecular cell 2010-12, Vol.40 (6), p.965-975
Hauptverfasser:	Zobeck, Katie L., Buckley, Martin S., Zipfel, Warren R., Lis, John T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - metabolism Cell Survival DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Drosophila Drosophila melanogaster - cytology Drosophila melanogaster - metabolism Drosophila Proteins - genetics Drosophila Proteins - metabolism Heat Shock Transcription Factors HSP70 Heat-Shock Proteins - metabolism Positive Transcriptional Elongation Factor B - genetics Positive Transcriptional Elongation Factor B - metabolism RNA Polymerase II - genetics RNA Polymerase II - metabolism Salivary Glands - cytology Salivary Glands - metabolism Time Factors Transcription Factors - genetics Transcription Factors - metabolism
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