Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO2 determination
An accurate SO 2 prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least squares fit. T...
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Veröffentlicht in: | Biomedical optics express 2010-10, Vol.1 (3), p.748-761 |
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creator | Zou, Fengmei Jin, Chunguang Ross, Randy R. Soller, Babs |
description | An accurate SO
2
prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least squares fit. This paper investigated the effect of potential spectral interferences that are likely to be encountered in clinical use, on SO
2
prediction accuracy. The factors include the concentration of hemoglobin in blood, the volume of blood and volume of water in the tissue under the sensor, reduced scattering coefficient, µ
s
', of the muscle, fat thickness and the source-detector spacing. The SO
2
prediction method was evaluated on simulated muscle spectra as well as on dual-dye phantoms which simulate the absorbance of oxygenated and deoxygenated hemoglobin. |
doi_str_mv | 10.1364/BOE.1.000748 |
format | Article |
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2
prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least squares fit. This paper investigated the effect of potential spectral interferences that are likely to be encountered in clinical use, on SO
2
prediction accuracy. The factors include the concentration of hemoglobin in blood, the volume of blood and volume of water in the tissue under the sensor, reduced scattering coefficient, µ
s
', of the muscle, fat thickness and the source-detector spacing. The SO
2
prediction method was evaluated on simulated muscle spectra as well as on dual-dye phantoms which simulate the absorbance of oxygenated and deoxygenated hemoglobin.</description><identifier>EISSN: 2156-7085</identifier><identifier>DOI: 10.1364/BOE.1.000748</identifier><identifier>PMID: 21258506</identifier><language>eng</language><publisher>Optical Society of America</publisher><subject>Spectroscopic Diagnostics</subject><ispartof>Biomedical optics express, 2010-10, Vol.1 (3), p.748-761</ispartof><rights>2010 Optical Society of America 2010 OSA</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018045/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018045/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,883,27907,27908,53774,53776</link.rule.ids></links><search><creatorcontrib>Zou, Fengmei</creatorcontrib><creatorcontrib>Jin, Chunguang</creatorcontrib><creatorcontrib>Ross, Randy R.</creatorcontrib><creatorcontrib>Soller, Babs</creatorcontrib><title>Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO2 determination</title><title>Biomedical optics express</title><description>An accurate SO
2
prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least squares fit. This paper investigated the effect of potential spectral interferences that are likely to be encountered in clinical use, on SO
2
prediction accuracy. The factors include the concentration of hemoglobin in blood, the volume of blood and volume of water in the tissue under the sensor, reduced scattering coefficient, µ
s
', of the muscle, fat thickness and the source-detector spacing. The SO
2
prediction method was evaluated on simulated muscle spectra as well as on dual-dye phantoms which simulate the absorbance of oxygenated and deoxygenated hemoglobin.</description><subject>Spectroscopic Diagnostics</subject><issn>2156-7085</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNpVj8tKAzEYhYMgttTufIC8wNRcJ5mNoKXaQrFgFZdDJvnTRtrMMEkLfXtbdePqwLl8cBC6o2RCeSnun1azCZ0QQpTQV2jIqCwLRbQcoHFKX2efCKEI1zdowCiTWpJyiGARj5By2Jgc2ohbj1MHNvdmh0PM0HvoIVpI-BzmLWBj7aE39nRpNn1rXGOiw9PP4nXxtsY5pHQAvF4x7OC83of4w71F197sEoz_dIQ-nmfv03mxXL0spo_LomOU5MIxRTlQIZVX0jTE88oySSrtBVSSsobQUrqqMZo5WlqjS5C-UlYrLrxrKB-hh19ud2j24CzEy5O668Pe9Ke6NaH-n8SwrTftseaEaiIk_wY-0GN5</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Zou, Fengmei</creator><creator>Jin, Chunguang</creator><creator>Ross, Randy R.</creator><creator>Soller, Babs</creator><general>Optical Society of America</general><scope>5PM</scope></search><sort><creationdate>20101001</creationdate><title>Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO2 determination</title><author>Zou, Fengmei ; Jin, Chunguang ; Ross, Randy R. ; Soller, Babs</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p210t-d2713e1457f75ab0f39c25098f4e9512b0165d9ba82d16ca86e5f97c8734fdb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Spectroscopic Diagnostics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zou, Fengmei</creatorcontrib><creatorcontrib>Jin, Chunguang</creatorcontrib><creatorcontrib>Ross, Randy R.</creatorcontrib><creatorcontrib>Soller, Babs</creatorcontrib><collection>PubMed Central (Full Participant titles)</collection><jtitle>Biomedical optics express</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zou, Fengmei</au><au>Jin, Chunguang</au><au>Ross, Randy R.</au><au>Soller, Babs</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO2 determination</atitle><jtitle>Biomedical optics express</jtitle><date>2010-10-01</date><risdate>2010</risdate><volume>1</volume><issue>3</issue><spage>748</spage><epage>761</epage><pages>748-761</pages><eissn>2156-7085</eissn><abstract>An accurate SO
2
prediction method for using broadband continuous-wave diffuse reflectance near infrared (NIR) spectroscopy is proposed. The method fitted the NIR spectra to a Taylor expansion attenuation model, and used the simulated annealing method to initialize the nonlinear least squares fit. This paper investigated the effect of potential spectral interferences that are likely to be encountered in clinical use, on SO
2
prediction accuracy. The factors include the concentration of hemoglobin in blood, the volume of blood and volume of water in the tissue under the sensor, reduced scattering coefficient, µ
s
', of the muscle, fat thickness and the source-detector spacing. The SO
2
prediction method was evaluated on simulated muscle spectra as well as on dual-dye phantoms which simulate the absorbance of oxygenated and deoxygenated hemoglobin.</abstract><pub>Optical Society of America</pub><pmid>21258506</pmid><doi>10.1364/BOE.1.000748</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Spectroscopic Diagnostics |
title | Investigation of spectral interferences on the accuracy of broadband CW-NIRS tissue SO2 determination |
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