Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals

Recent studies reveal that maturation of the 40S ribosomal subunit precursors in mammals includes an additional step during processing of the internal transcribed spacer 1 (ITS1), when compared with yeast Saccharomyces cerevisiae, even though the protein content of the pre-40S particle appears to be...

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Veröffentlicht in:	Nucleic acids research 2011-01, Vol.39 (1), p.280-291
Hauptverfasser:	Carron, Coralie, O'Donohue, Marie-Françoise, Choesmel, Valérie, Faubladier, Marlène, Gleizes, Pierre-Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Active Transport, Cell Nucleus Biochemistry, Molecular Biology Biological Evolution Cell Adhesion Molecules Cell Adhesion Molecules - antagonists & inhibitors Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - physiology Cell Nucleus Cell Nucleus - metabolism Gene Knockdown Techniques HeLa Cells Humans Life Sciences Nuclear Proteins Nuclear Proteins - chemistry Ribosomal Proteins Ribosomal Proteins - antagonists & inhibitors Ribosomal Proteins - chemistry Ribosomal Proteins - physiology Ribosome Subunits, Small, Eukaryotic Ribosome Subunits, Small, Eukaryotic - metabolism RNA RNA Precursors RNA Precursors - metabolism RNA Processing, Post-Transcriptional RNA, Ribosomal RNA, Ribosomal - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Saccharomyces cerevisiae Proteins - chemistry Sequence Homology, Amino Acid
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