NOA1 is an essential GTPase required for mitochondrial protein synthesis

Nitric oxide associated-1 (NOA1) is an evolutionarily conserved guanosine triphosphate (GTP) binding protein that localizes predominantly to mitochondria in mammalian cells. On the basis of bioinformatic analysis, we predicted its possible involvement in ribosomal biogenesis, although this had not b...

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Veröffentlicht in:	Molecular biology of the cell 2011-01, Vol.22 (1), p.1-11
Hauptverfasser:	Kolanczyk, Mateusz, Pech, Markus, Zemojtel, Tomasz, Yamamoto, Hiroshi, Mikula, Ivan, Calvaruso, Maria-Antonietta, van den Brand, Mariël, Richter, Ricarda, Fischer, Bjoern, Ritz, Anita, Kossler, Nadine, Thurisch, Boris, Spoerle, Ralf, Smeitink, Jan, Kornak, Uwe, Chan, Danny, Vingron, Martin, Martasek, Pavel, Lightowlers, Robert N, Nijtmans, Leo, Schuelke, Markus, Nierhaus, Knud H, Mundlos, Stefan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - biosynthesis Animals Apoptosis Cells, Cultured Embryo, Mammalian - abnormalities Embryonic Development Fetal Death Fibroblasts GTP Phosphohydrolases - genetics GTP Phosphohydrolases - metabolism Humans In Situ Hybridization Mice Mice, Knockout Mitochondria - metabolism Mitochondrial Proteins - biosynthesis Oxidative Phosphorylation Protein Biosynthesis - genetics Ribosomes - metabolism RNA, Small Interfering Staurosporine - metabolism
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