Glutamine transport in rat kidney mitochondria in metabolic acidosis

In order to study factors regulating renal ammoniagenesis, the transport and metabolism of L-glutamine were studied in mitochondria from kidneys of control and acidotic rats. On incubation in 1 mM [(14)C]glutamine, there was production and accumulation of [(14)C]glutamate within the matrix space. Ho...

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Veröffentlicht in:	The Journal of clinical investigation 1974-07, Vol.54 (1), p.165-174
Hauptverfasser:	Adam, W, Simpson, D P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates - metabolism Acidosis - metabolism Ammonia - biosynthesis Animals Biological Transport, Active Carbon Radioisotopes Chronic Disease Furosemide - pharmacology Glutamates - metabolism Glutamine - metabolism Ketoglutaric Acids - metabolism Kidney - cytology Kidney - drug effects Kidney - metabolism Mitochondria - metabolism Oxygen Consumption Potassium - metabolism Rats Sodium - metabolism Time Factors Tritium
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