Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration

The most common cause of hereditary nephrogenic diabetes insipidus is a nonfunctional vasopressin (VP) receptor type 2 (V2R). Calcitonin, another ligand of G-protein-coupled receptors, has a VP-like effect on electrolytes and water reabsorption, suggesting that it may affect AQP2 trafficking. Here,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society of Nephrology 2011, Vol.22 (1), p.59-72
Hauptverfasser:	BOULEY, Richard, LU, Hua A. J, NUNES, Paula, DA SILVA, Nicolas, MCLAUGHLIN, Margaret, YING CHEN, BROWN, Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquaporin 2 - metabolism Basic Research Biological and medical sciences Calcitonin - pharmacology Cell Membrane - drug effects Cell Membrane - metabolism Cyclic AMP - metabolism Endocytosis - drug effects Endocytosis - physiology Exocytosis - drug effects Exocytosis - physiology Fundamental and applied biological sciences. Psychology Kidney - cytology Kidney - drug effects Kidney - metabolism LLC-PK1 Cells Male Medical sciences Models, Animal Nephrology. Urinary tract diseases Osmolar Concentration Protein Transport - drug effects Protein Transport - physiology Rats Rats, Brattleboro Swine Urine - physiology Vasopressins - pharmacology Vertebrates: urinary system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!