Chronic Uremia Stimulates LDL Carbamylation and Atherosclerosis

Carbamylated LDL (cLDL) is a potential atherogenic factor in chronic kidney disease (CKD). However, whether elevated plasma cLDL associates with atherosclerosis in vivo is unknown. Here, we induced CKD surgically in apolipoprotein E-deficient (ApoE(-/-)) mice fed a high-fat diet to promote the devel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American Society of Nephrology 2010-11, Vol.21 (11), p.1852-1857
Hauptverfasser:	APOSTOLOV, Eugene O, RAY, Debarti, SAVENKA, Alena V, SHAH, Sudhir V, BASNAKIAN, Alexei G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apolipoproteins E - deficiency Apolipoproteins E - genetics Atherosclerosis (general aspects, experimental research) Atherosclerosis - blood Atherosclerosis - chemically induced Atherosclerosis - epidemiology Biological and medical sciences Blood and lymphatic vessels Brief Communications Cardiology. Vascular system Chronic Disease Dietary Fats - adverse effects Disease Models, Animal Intercellular Adhesion Molecule-1 - blood Kidney Diseases - blood Kidney Diseases - complications Kidney Diseases - etiology Lipoproteins, LDL - blood Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Nephrectomy - adverse effects Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Renal failure Risk Factors Urea - adverse effects Uremia - blood Uremia - chemically induced Uremia - complications
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!