Phospholipase D controls Dictyostelium development by regulating G protein signaling

Dictyostelium discoideum cells normally exist as individual amoebae, but will enter a period of multicellular development upon starvation. The initial stages of development involve the aggregation of individual cells, using cAMP as a chemoattractant. Chemotaxis is initiated when cAMP binds to its re...

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Veröffentlicht in:	Cellular signalling 2011-02, Vol.23 (2), p.335-343
Hauptverfasser:	Ray, Sibnath, Chen, Yi, Ayoung, Joanna, Hanna, Rachel, Brazill, Derrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemotaxis Cyclic AMP - physiology Development Dictyostelium Dictyostelium - enzymology Dictyostelium - growth & development FRET G protein GTP-Binding Protein Regulators - physiology GTP-Binding Proteins - physiology Phosphatidic Acids - biosynthesis Phospholipase D - physiology PLD Quorum Sensing Receptors, Cyclic AMP - metabolism Signal Transduction
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