Epidemiology and clinical course of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiolog...
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| Veröffentlicht in: | European journal of heart failure 2011-01, Vol.13 (1), p.18-28 |
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| container_title | European journal of heart failure |
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| creator | Lam, Carolyn S.P. Donal, Erwan Kraigher-Krainer, Elisabeth Vasan, Ramachandran S. |
| description | Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent studies have provided detailed characterization of larger numbers of patients with HFPEF than ever before. This review summarizes the state of current knowledge with regards to the disease burden, patient characteristics, clinical course, and outcomes of HFPEF. Despite the wealth of available data, substantive gaps in knowledge were identified. These gaps represent opportunities for further research in HFPEF, a syndrome that is clearly a rising societal burden and that is associated with substantial morbidity and mortality. |
| doi_str_mv | 10.1093/eurjhf/hfq121 |
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Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent studies have provided detailed characterization of larger numbers of patients with HFPEF than ever before. This review summarizes the state of current knowledge with regards to the disease burden, patient characteristics, clinical course, and outcomes of HFPEF. Despite the wealth of available data, substantive gaps in knowledge were identified. These gaps represent opportunities for further research in HFPEF, a syndrome that is clearly a rising societal burden and that is associated with substantial morbidity and mortality.</description><identifier>ISSN: 1388-9842</identifier><identifier>EISSN: 1879-0844</identifier><identifier>DOI: 10.1093/eurjhf/hfq121</identifier><identifier>PMID: 20685685</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Bioengineering ; Cardiology and cardiovascular system ; Disease Progression ; Epidemiology ; Europe ; Europe - epidemiology ; Heart Failure ; Heart Failure - diagnostic imaging ; Heart Failure - epidemiology ; Heart Failure - pathology ; Heart failure with preserved ejection fraction ; Hemodynamics ; Human health and pathology ; Humans ; Incidence ; Life Sciences ; Mortality ; Prevalence ; Public Health ; Review ; Risk Factors ; Stroke Volume ; Ultrasonography ; United States ; United States - epidemiology ; Ventricular Function, Left</subject><ispartof>European journal of heart failure, 2011-01, Vol.13 (1), p.18-28</ispartof><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © 2011 the Authors</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><rights>Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2010. For permissions please email: journals.permissions@oxfordjournals.org. 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5481-d76c147562f8bd18b36320a8a9bd6f2541f6dfc5690c94090400464ecc917e4d3</citedby><cites>FETCH-LOGICAL-c5481-d76c147562f8bd18b36320a8a9bd6f2541f6dfc5690c94090400464ecc917e4d3</cites><orcidid>0000-0003-2677-3389 ; 0000-0002-9083-1582</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1093%2Feurjhf%2Fhfq121$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1093%2Feurjhf%2Fhfq121$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,776,780,881,1411,1427,27901,27902,45550,45551,46384,46808</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20685685$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-00907648$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Lam, Carolyn S.P.</creatorcontrib><creatorcontrib>Donal, Erwan</creatorcontrib><creatorcontrib>Kraigher-Krainer, Elisabeth</creatorcontrib><creatorcontrib>Vasan, Ramachandran S.</creatorcontrib><title>Epidemiology and clinical course of heart failure with preserved ejection fraction</title><title>European journal of heart failure</title><addtitle>European Journal of Heart Failure</addtitle><description>Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent studies have provided detailed characterization of larger numbers of patients with HFPEF than ever before. This review summarizes the state of current knowledge with regards to the disease burden, patient characteristics, clinical course, and outcomes of HFPEF. Despite the wealth of available data, substantive gaps in knowledge were identified. These gaps represent opportunities for further research in HFPEF, a syndrome that is clearly a rising societal burden and that is associated with substantial morbidity and mortality.</description><subject>Bioengineering</subject><subject>Cardiology and cardiovascular system</subject><subject>Disease Progression</subject><subject>Epidemiology</subject><subject>Europe</subject><subject>Europe - epidemiology</subject><subject>Heart Failure</subject><subject>Heart Failure - diagnostic imaging</subject><subject>Heart Failure - epidemiology</subject><subject>Heart Failure - pathology</subject><subject>Heart failure with preserved ejection fraction</subject><subject>Hemodynamics</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Life Sciences</subject><subject>Mortality</subject><subject>Prevalence</subject><subject>Public Health</subject><subject>Review</subject><subject>Risk Factors</subject><subject>Stroke Volume</subject><subject>Ultrasonography</subject><subject>United States</subject><subject>United States - epidemiology</subject><subject>Ventricular Function, Left</subject><issn>1388-9842</issn><issn>1879-0844</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc9v0zAUxyMEYmNw5IpyQxyyPf-I41yQpqo_hipQJxASF8t1nheXNO7spKP_PRkpFXBAsuQn-_M-z9Y3SV4TuCRQsivsw6a2V7W9J5Q8Sc6JLMoMJOdPh5pJmZWS07PkRYwbAFIA0OfJGQUh82GdJ7fTnatw63zj7w6pbqvUNK51Rjep8X2ImHqb1qhDl1rtmj5g-uC6Ot0FjBj2WKW4QdM536Y26F_Fy-SZ1U3EV8f9Ivkym36eLLLlp_nN5HqZmZxLklWFMIQXuaBWrisi10wwClrqcl0JS3NOrKisyUUJpuRQAgfggqMxJSmQV-wieT96d_16i5XBtgu6UbvgtjoclNdO_X3Tulrd-b1iAIznbBC8GwX1P22L66V6PINhaiG43JOBfXscFvx9j7FTWxcNNo1u0fdRSQqFLCnIgcxG0gQfY0B7UhNQj5GpMTI1Rjbwb_78xon-ndEA5CPw4Bo8_N-mph8Ws8VsNYqPD3Gxwx-nPh2-K1GwIldfP87VZP7tVq5WoCj7Cd3HtYM</recordid><startdate>201101</startdate><enddate>201101</enddate><creator>Lam, Carolyn S.P.</creator><creator>Donal, Erwan</creator><creator>Kraigher-Krainer, Elisabeth</creator><creator>Vasan, Ramachandran S.</creator><general>Blackwell Publishing Ltd</general><general>European Society of Cardiology (Wiley)</general><general>Oxford University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2677-3389</orcidid><orcidid>https://orcid.org/0000-0002-9083-1582</orcidid></search><sort><creationdate>201101</creationdate><title>Epidemiology and clinical course of heart failure with preserved ejection fraction</title><author>Lam, Carolyn S.P. ; Donal, Erwan ; Kraigher-Krainer, Elisabeth ; Vasan, Ramachandran S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5481-d76c147562f8bd18b36320a8a9bd6f2541f6dfc5690c94090400464ecc917e4d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Bioengineering</topic><topic>Cardiology and cardiovascular system</topic><topic>Disease Progression</topic><topic>Epidemiology</topic><topic>Europe</topic><topic>Europe - epidemiology</topic><topic>Heart Failure</topic><topic>Heart Failure - diagnostic imaging</topic><topic>Heart Failure - epidemiology</topic><topic>Heart Failure - pathology</topic><topic>Heart failure with preserved ejection fraction</topic><topic>Hemodynamics</topic><topic>Human health and pathology</topic><topic>Humans</topic><topic>Incidence</topic><topic>Life Sciences</topic><topic>Mortality</topic><topic>Prevalence</topic><topic>Public Health</topic><topic>Review</topic><topic>Risk Factors</topic><topic>Stroke Volume</topic><topic>Ultrasonography</topic><topic>United States</topic><topic>United States - epidemiology</topic><topic>Ventricular Function, Left</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lam, Carolyn S.P.</creatorcontrib><creatorcontrib>Donal, Erwan</creatorcontrib><creatorcontrib>Kraigher-Krainer, Elisabeth</creatorcontrib><creatorcontrib>Vasan, Ramachandran S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>European journal of heart failure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lam, Carolyn S.P.</au><au>Donal, Erwan</au><au>Kraigher-Krainer, Elisabeth</au><au>Vasan, Ramachandran S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epidemiology and clinical course of heart failure with preserved ejection fraction</atitle><jtitle>European journal of heart failure</jtitle><addtitle>European Journal of Heart Failure</addtitle><date>2011-01</date><risdate>2011</risdate><volume>13</volume><issue>1</issue><spage>18</spage><epage>28</epage><pages>18-28</pages><issn>1388-9842</issn><eissn>1879-0844</eissn><abstract>Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major public health problem worldwide. Significant advances have been made in our understanding of the epidemiology of HFPEF over the past two decades, with the publication of numerous population‐based epidemiological studies, large heart failure registries, and randomized clinical trials. These recent studies have provided detailed characterization of larger numbers of patients with HFPEF than ever before. This review summarizes the state of current knowledge with regards to the disease burden, patient characteristics, clinical course, and outcomes of HFPEF. Despite the wealth of available data, substantive gaps in knowledge were identified. These gaps represent opportunities for further research in HFPEF, a syndrome that is clearly a rising societal burden and that is associated with substantial morbidity and mortality.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>20685685</pmid><doi>10.1093/eurjhf/hfq121</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2677-3389</orcidid><orcidid>https://orcid.org/0000-0002-9083-1582</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Wiley Online Library - AutoHoldings Journals; MEDLINE; Wiley Online Library Free Content; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Bioengineering Cardiology and cardiovascular system Disease Progression Epidemiology Europe Europe - epidemiology Heart Failure Heart Failure - diagnostic imaging Heart Failure - epidemiology Heart Failure - pathology Heart failure with preserved ejection fraction Hemodynamics Human health and pathology Humans Incidence Life Sciences Mortality Prevalence Public Health Review Risk Factors Stroke Volume Ultrasonography United States United States - epidemiology Ventricular Function, Left |
| title | Epidemiology and clinical course of heart failure with preserved ejection fraction |
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