Increased fatigue resistance linked to Ca2+‐stimulated mitochondrial biogenesis in muscle fibres of cold‐acclimated mice

Mammals exposed to a cold environment initially generate heat by repetitive muscle activity (shivering). Shivering is successively replaced by the recruitment of uncoupling protein‐1 (UCP1)‐dependent heat production in brown adipose tissue. Interestingly, adaptations observed in skeletal muscles of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of physiology 2010-11, Vol.588 (21), p.4275-4288
Hauptverfasser:	Bruton, Joseph D., Aydin, Jan, Yamada, Takashi, Shabalina, Irina G., Ivarsson, Niklas, Zhang, Shi‐Jin, Wada, Masanobu, Tavi, Pasi, Nedergaard, Jan, Katz, Abram, Westerblad, Håkan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological - physiology Animals Calcium - physiology Cold Temperature Female Ion Channels - genetics Ion Channels - physiology Mice Mice, Inbred C57BL Mice, Knockout Mitochondria, Muscle - physiology Mitochondrial Proteins - genetics Mitochondrial Proteins - physiology Models, Animal Muscle Fatigue - physiology Muscle Fibers, Skeletal - physiology Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha Shivering - physiology Skeletal Muscle and Exercise Trans-Activators - physiology Transcription Factors Uncoupling Protein 1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!