Human catestatin peptides differentially regulate infarct size in the ischemic–reperfused rat heart

In acute myocardial infarction increased plasma levels of chromogranin A are correlated with decreased survival. At the human chromogranin A gene locus there are two naturally occurring amino acid substitution variants within the catestatin region, i.e. Gly 364Ser and Pro 370Leu, displaying differen...

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Veröffentlicht in:	Regulatory peptides 2010-11, Vol.165 (1), p.63-70
Hauptverfasser:	Brar, Bhawanjit K., Helgeland, Erik, Mahata, Sushil K., Zhang, Kuixing, O'Connor, Daniel T., Helle, Karen B., Jonassen, Anne K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Catestatin Cells, Cultured Chromogranin A Chromogranin A - metabolism Chromogranin A - pharmacology Humans Infarction Ischemia Male Mice Myocardial Infarction - metabolism Myocardial Reperfusion Injury - metabolism Myocardium - pathology Myocytes, Cardiac - drug effects Peptide Fragments - metabolism Peptide Fragments - pharmacology Phosphorylation - drug effects Rats Rats, Wistar Reperfusion
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