Collagen-based fibrous scaffold for spatial organization of encapsulated and seeded human mesenchymal stem cells

Abstract Living tissues consist of groups of cells organized in a controlled manner to perform a specific function. Spatial distribution of cells within a three-dimensional matrix is critical for the success of any tissue-engineering construct. Fibers endowed with cell-encapsulation capability would...

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Veröffentlicht in:	Biomaterials 2009-02, Vol.30 (6), p.1133-1142
Hauptverfasser:	Yow, S.Z, Quek, C.H, Yim, Evelyn K.F, Lim, C.T, Leong, K.W
Format:	Artikel
Sprache:	eng
Schlagworte:	3D cell patterning Advanced Basic Science Biomarkers - metabolism Cell encapsulation Cell Lineage - drug effects Cell Proliferation - drug effects Cell Survival - drug effects Collagen Cytoskeleton - drug effects Cytoskeleton - metabolism Dentistry Electrolytes Fibrillar Collagens - pharmacology Fibrillar Collagens - ultrastructure Fibrous scaffold Gene Expression Regulation - drug effects Humans Mechanics Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Microscopy, Atomic Force Polymers - pharmacology Quantum Dots RNA, Messenger - genetics RNA, Messenger - metabolism Stem cell tissue engineering Tissue Scaffolds
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