Tertiary Aminourea-Catalyzed Enantioselective Iodolactonization

Binding the anion: A highly enantioselective iodolactonization of 5‐hexenoic acids has been achieved using a tertiary aminourea‐catalyst (see scheme). The use of catalytic iodine in this process is critical to enhancing both the reactivity and enantioselectivity of the stoichiometric I+ source. The...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 2010-09, Vol.49 (40), p.7332-7335
Hauptverfasser:	Veitch, Gemma E, Jacobsen, Eric N
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines - chemistry anion binding asymmetric catalysis Catalysis halogenation Iodine - chemistry iodolactonization Lactones - chemistry Molecular Structure organocatalysis Stereoisomerism Urea - chemistry
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