Grassypeptolides A−C, Cytotoxic Bis-thiazoline Containing Marine Cyclodepsipeptides

Grassypeptolides A−C (1−3), a group of closely related bis-thiazoline containing cyclic depsipeptides, have been isolated from extracts of the marine cyanobacterium Lyngbya confervoides. Although structural differences between the analogues are minimal, comparison of the in vitro cytotoxicity of the...

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Veröffentlicht in:	Journal of organic chemistry 2010-12, Vol.75 (23), p.8012-8023
Hauptverfasser:	Kwan, Jason C, Ratnayake, Ranjala, Abboud, Khalil A, Paul, Valerie J, Luesch, Hendrik
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioconversions. Hemisynthesis Biological and medical sciences Biotechnology Cell Cycle Chemistry Crystallography, X-Ray Cyanobacteria - chemistry Depsipeptides - chemistry Depsipeptides - isolation & purification Depsipeptides - pharmacology Exact sciences and technology Fundamental and applied biological sciences. Psychology G1 Phase Heterocyclic compounds Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms Inhibitory Concentration 50 Magnetic Resonance Spectroscopy Marine Toxins - chemistry Methods. Procedures. Technologies Molecular Conformation Molecular Structure Organic chemistry Peptides Preparations and properties Structure-Activity Relationship
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