Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease

Genome wide association studies, replicated by numerous well powered validation studies, have revealed a large number of loci likely to play a role in susceptibility to many multifactorial diseases. It is now well established that some of these loci are shared between diseases with similar aetiology...

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Veröffentlicht in:	Arthritis research & therapy 2010-01, Vol.12 (5), p.R175-R175, Article R175
Hauptverfasser:	Eyre, Stephen, Hinks, Anne, Bowes, John, Flynn, Edward, Martin, Paul, Wilson, Anthony G, Morgan, Ann W, Emery, Paul, Steer, Sophia, Hocking, Lynne J, Reid, David M, Harrison, Pille, Wordsworth, Paul, Thomson, Wendy, Worthington, Jane, Barton, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arthritis, Rheumatoid - genetics Celiac disease Celiac Disease - genetics Diabetes Mellitus, Type 1 - genetics Female Genetic aspects Genetic Predisposition to Disease - genetics Genetic susceptibility Genotype GTPase-Activating Proteins - genetics Humans Male Middle Aged Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide Rheumatoid arthritis Risk factors Type 1 diabetes
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