The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid
Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega (ω)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascu...
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| Veröffentlicht in: | Canadian journal of cardiology 2010-11, Vol.26 (9), p.489-496 |
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| container_title | Canadian journal of cardiology |
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| creator | Rodriguez-Leyva, Delfin, MD PhD Bassett, Chantal M.C., PhD McCullough, Richelle, BSc Pierce, Grant N., PhD |
| description | Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. The increased use of omega (ω)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of ω-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based ω-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown. |
| doi_str_mv | 10.1016/S0828-282X(10)70455-4 |
| format | Article |
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The increased use of omega (ω)-3 fatty acids is a powerful example of one such nutritional strategy that may produce significant cardiovascular benefits. Marine food products have provided the traditional dietary sources of ω-3 fatty acids. Flaxseed is an alternative to marine products. It is one of the richest sources of the plant-based ω-3 fatty acid, alpha-linolenic acid (ALA). Based on the results of clinical trials, epidemiological investigations and experimental studies, ingestion of ALA has been suggested to have a positive impact on CVD. Because of its high ALA content, the use of flaxseed has been advocated to combat CVD. The purpose of the present review was to identify the known cardiovascular effects of flaxseed and ALA and, just as importantly, what is presently unknown.</description><subject>alpha-Linolenic Acid - administration & dosage</subject><subject>alpha-Linolenic Acid - therapeutic use</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Clinical Trials as Topic</subject><subject>Evidence-Based Medicine</subject><subject>Fibre</subject><subject>Fish</subject><subject>Flax</subject><subject>Heart disease</subject><subject>Humans</subject><subject>Lignans</subject><subject>Nutrition</subject><subject>Phytotherapy</subject><subject>Polyunsaturated fatty acids</subject><subject>Review</subject><subject>Seeds</subject><subject>Treatment Outcome</subject><issn>0828-282X</issn><issn>1916-7075</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi0EokvhJ4Byg0qk-Ct2cilCFRSkShwogps1ccZdF2-82Mmq--9JdtsV9MLJ0vidZ0bzEPKS0VNGmXr3jda8LnnNf75h9ERTWVWlfEQWrGGq1FRXj8niEDkiz3K-oVQyrdVTcsQZ1UpzsSA_rpZYWEidjxvIdgyQCnQO7ZCL6AoX4DYjdgX0XeHn2gqvoRSFg2HYFmB997aAsF5CGXwfA_be7qrPyRMHIeOLu_eYfP_08er8c3n59eLL-YfL0irRDKWTSgmnbas4a6yrWyl5RSUAdIJpi9gqIWxtG9dw1knQHClted2CbB2thDgmZ3vuemxX2FnshwTBrJNfQdqaCN78-9P7pbmOG8ObuhGVmgCv7wAp_h4xD2bls8UQoMc4ZqNrTUWtmZ6S1T5pU8w5oTtMYdTMTszOiZkPPpd2Toyc-l79veKh617CFHi_D-B0qI3HZLL12FvsfJpEmC76_444e0Cwkw5vIfzCLeabOKZ-smCYydzQPWRmTBvMBCn-ANcUsm0</recordid><startdate>20101101</startdate><enddate>20101101</enddate><creator>Rodriguez-Leyva, Delfin, MD PhD</creator><creator>Bassett, Chantal M.C., PhD</creator><creator>McCullough, Richelle, BSc</creator><creator>Pierce, Grant N., PhD</creator><general>Elsevier Inc</general><general>Pulsus Group Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20101101</creationdate><title>The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid</title><author>Rodriguez-Leyva, Delfin, MD PhD ; Bassett, Chantal M.C., PhD ; McCullough, Richelle, BSc ; Pierce, Grant N., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c639t-f4663f7cb6219cf8b442504aaad317ceeb633c8c9f921d4a72e00b28ba4bf0533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>alpha-Linolenic Acid - administration & dosage</topic><topic>alpha-Linolenic Acid - therapeutic use</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Clinical Trials as Topic</topic><topic>Evidence-Based Medicine</topic><topic>Fibre</topic><topic>Fish</topic><topic>Flax</topic><topic>Heart disease</topic><topic>Humans</topic><topic>Lignans</topic><topic>Nutrition</topic><topic>Phytotherapy</topic><topic>Polyunsaturated fatty acids</topic><topic>Review</topic><topic>Seeds</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodriguez-Leyva, Delfin, MD PhD</creatorcontrib><creatorcontrib>Bassett, Chantal M.C., PhD</creatorcontrib><creatorcontrib>McCullough, Richelle, BSc</creatorcontrib><creatorcontrib>Pierce, Grant N., PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rodriguez-Leyva, Delfin, MD PhD</au><au>Bassett, Chantal M.C., PhD</au><au>McCullough, Richelle, BSc</au><au>Pierce, Grant N., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid</atitle><jtitle>Canadian journal of cardiology</jtitle><addtitle>Can J Cardiol</addtitle><date>2010-11-01</date><risdate>2010</risdate><volume>26</volume><issue>9</issue><spage>489</spage><epage>496</epage><pages>489-496</pages><issn>0828-282X</issn><eissn>1916-7075</eissn><abstract>Preventing the occurrence of cardiovascular disease (CVD) with nutritional interventions is a therapeutic strategy that may warrant greater research attention. 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| ispartof | Canadian journal of cardiology, 2010-11, Vol.26 (9), p.489-496 |
| issn | 0828-282X 1916-7075 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | alpha-Linolenic Acid - administration & dosage alpha-Linolenic Acid - therapeutic use Cardiovascular Cardiovascular disease Cardiovascular Diseases - prevention & control Clinical Trials as Topic Evidence-Based Medicine Fibre Fish Flax Heart disease Humans Lignans Nutrition Phytotherapy Polyunsaturated fatty acids Review Seeds Treatment Outcome |
| title | The cardiovascular effects of flaxseed and its omega-3 fatty acid, alpha-linolenic acid |
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