The BRCAPRO 5.0 model is a useful tool in genetic counseling and clinical management of male breast cancer cases

No study has evaluated the performance of BRCA1/2 mutations prediction models in male breast cancer (MBC) series. Although rare, MBC deserves attention because male and female breast cancers share many characteristics, including the involvement of genetic predisposition factors such as BRCA1 / BRCA2...

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Veröffentlicht in:	European journal of human genetics : EJHG 2010-07, Vol.18 (7), p.856-858
Hauptverfasser:	Zanna, Ines, Rizzolo, Piera, Sera, Francesco, Falchetti, Mario, Aretini, Paolo, Giannini, Giuseppe, Masala, Giovanna, Gulino, Alberto, Palli, Domenico, Ottini, Laura
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/2489 631/67/1347 692/700/228/2050/1510 Area Under Curve Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedicine BRCA1 protein BRCA2 protein Breast cancer Breast Neoplasms, Male - genetics Breast Neoplasms, Male - therapy Cytogenetics Family medical history Female Fundamental and applied biological sciences. Psychology Gene Expression General aspects. Genetic counseling Genetic Counseling - methods Genetics of eukaryotes. Biological and molecular evolution Gynecology. Andrology. Obstetrics Health risk assessment Human Genetics Humans Male Mammary gland diseases Medical genetics Medical sciences Models, Genetic Molecular and cellular biology Mutation Ovarian cancer ROC Curve Short Report Software Tumors
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