Methionine synthase A2756G polymorphism and cancer risk: a meta-analysis

Polymorphisms in methionine synthase ( MTR ) gene may be involved in carcinogenesis by affecting DNA methylation. However, association studies on MTR A2756G polymorphism in cancers have reported conflicting results. Therefore we performed a meta-analysis to better assess the associations. A total of...

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Veröffentlicht in:	European journal of human genetics : EJHG 2010-03, Vol.18 (3), p.370-378
Hauptverfasser:	Yu, Ke, Zhang, Jing, Zhang, Jiyuan, Dou, Chao, Gu, Shaohua, Xie, Yi, Mao, Yumin, Ji, Chaoneng
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methyltetrahydrofolate-homocysteine S-methyltransferase 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase - genetics Acute lymphatic leukemia Amino Acid Substitution - genetics Asian Continental Ancestry Group - genetics Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedicine Carcinogenesis Colorectal carcinoma Cytogenetics DNA methylation Environmental factors Ethnic groups Europe Fundamental and applied biological sciences. Psychology Gene Expression Gene polymorphism General aspects. Genetic counseling Genetic engineering Genetic Heterogeneity Genetic Predisposition to Disease - genetics Genetics of eukaryotes. Biological and molecular evolution Health risk assessment Human Genetics Humans Lymphatic leukemia Medical genetics Medical sciences Methionine Methylation Molecular and cellular biology Neoplasms - enzymology Neoplasms - genetics Odds Ratio Polymorphism Polymorphism, Single Nucleotide - genetics Population studies Publication Bias Studies
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