The DLX1and DLX2 genes and susceptibility to autism spectrum disorders

An imbalance between excitation and inhibition in the cerebral cortex has been suggested as a possible etiology of autism. The DLX genes encode homeodomain-containing transcription factors controlling the generation of GABAergic cortical interneurons. The DLX1 and DLX2 genes lie head-to-head in 2q32...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of human genetics : EJHG 2009-02, Vol.17 (2), p.228-235
Hauptverfasser:	Liu, Xudong, Novosedlik, Natalia, Wang, Ami, Hudson, Melissa L, Cohen, Ira L, Chudley, Albert E, Forster-Gibson, Cynthia J, Lewis, Suzanne M E, Holden, Jeanette J A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Autism Autistic Disorder - genetics Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedicine Brain research Child clinical studies Chromosome 2 Cohort Studies Cortex Cytogenetics Developmental disorders Epilepsy Etiology Family Fundamental and applied biological sciences. Psychology Gene Expression General aspects. Genetic counseling Genes Genetic Predisposition to Disease Genetics Genetics of eukaryotes. Biological and molecular evolution Haplotypes Homeobox Homeodomain Proteins - genetics Human Genetics Humans Hypotheses Infantile autism Interneurons Medical genetics Medical sciences Molecular and cellular biology Mutation Neurobiology Physiology Polymorphism, Single Nucleotide Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Single-nucleotide polymorphism Transcription factors Transcription Factors - genetics γ-Aminobutyric acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!