A pharmacological functional magnetic resonance imaging study probing the interface of cognitive and emotional brain systems in pediatric bipolar disorder

This functional magnetic resonance imaging (fMRI) study investigated the effects of pharmacotherapy on brain function underlying affect dysregulation and cognitive function in pediatric bipolar disorder (PBD). Healthy controls (HC) (n=14; mean age =14.1 ± 2.4 years) and unmedicated PBD patients with...

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Veröffentlicht in:	Journal of child and adolescent psychopharmacology 2010-10, Vol.20 (5), p.395-406
Hauptverfasser:	Pavuluri, Mani N, Passarotti, Alessandra M, Parnes, Stephanie A, Fitzgerald, Jacklynn M, Sweeney, John A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Affect - drug effects Affect - physiology Antipsychotic Agents - therapeutic use Antipsychotic drugs Attention - drug effects Attention - physiology Bipolar disorder Bipolar Disorder - diagnosis Bipolar Disorder - drug therapy Bipolar Disorder - physiopathology Bipolar Disorder - psychology Brain Brain - drug effects Brain - physiopathology Care and treatment Case-Control Studies Child Child psychopathology Cognition & reasoning Cognition - drug effects Cognition - physiology Dosage and administration Emotions Emotions - drug effects Emotions - physiology Female Gyrus Cinguli - physiopathology Humans Interfaces Magnetic Resonance Imaging Male Methods Neuropsychological Tests NMR Nuclear magnetic resonance Original Parahippocampal Gyrus - physiopathology Parietal Lobe - physiopathology Patient outcomes Pharmacology Physiological aspects Prefrontal Cortex - physiopathology Triazines - therapeutic use
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