Paraoxon-Induced Protein Expression Changes to SH-SY5Y Cells

SH-SY5Y neuroblastoma cells were examined to determine changes in protein expression following exposure to the organophosphate paraoxon (O,O-diethyl-p-nitrophenoxy phosphate). Exposure of SH-SY5Y cells to paraoxon (20 μM) for 48 h showed no significant change in cell viability as established using a...

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Veröffentlicht in:	Chemical research in toxicology 2010-11, Vol.23 (11), p.1656-1662
Hauptverfasser:	Prins, John M, George, Kathleen M, Thompson, Charles M
Format:	Artikel
Sprache:	eng
Schlagworte:	Blotting, Western Cell Line, Tumor Electrophoresis, Gel, Two-Dimensional Heterogeneous-Nuclear Ribonucleoprotein Group C - metabolism HSP90 Heat-Shock Proteins - metabolism Humans Insecticides - chemistry Insecticides - toxicity Paraoxon - chemistry Paraoxon - toxicity Proteome - drug effects Proteome - metabolism Proton-Translocating ATPases - metabolism Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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