In Vivo Therapeutic Gas Delivery for Neuroprotection With Echogenic Liposomes

Ischemia-related neurological injury is a primary cause of stroke disability. Studies have demonstrated that xenon (Xe) may have potential as an effective and nontoxic neuroprotectant. Xe delivery is, however, hampered by lack of suitable administration methods. We have developed a pressurization-fr...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2010-10, Vol.122 (16), p.1578-1587
Hauptverfasser:	BRITTON, George L, KIM, Hyunggun, KEE, Patrick H, ARONOWSKI, Jaroslaw, HOLLAND, Christy K, MCPHERSON, David D, HUANG, Shao-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood and lymphatic vessels Brain Ischemia - etiology Brain Ischemia - prevention & control Cardiology. Vascular system Cell Survival - physiology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Drug Delivery Systems - methods Infarction, Middle Cerebral Artery - complications Injections, Intravenous Liposomes Male Medical sciences Models, Animal Neurons - cytology Neurons - physiology Pneumology Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases Rats Rats, Sprague-Dawley Reperfusion Injury - etiology Reperfusion Injury - prevention & control Ultrasonography Xenon - administration & dosage
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