Estimating the Number of Droplets and Drug Particles Emitted from MDIs

The objective of this paper is to assess the number of drug particles or droplets contained in metered dose inhaler (MDI) aerosols. Equations were developed to estimate this. The number of drug particles was estimated to be as high as about 300 million for QVAR® solution MDIs and as low as 670,000 f...

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Veröffentlicht in:	AAPS PharmSciTech 2008-03, Vol.9 (1), p.112-115
1. Verfasser:	Stein, Stephen W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols - chemistry Anti-Asthmatic Agents - administration & dosage Anti-Asthmatic Agents - chemistry Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Colloids - chemistry Computer Simulation Drug Evaluation, Preclinical Metered Dose Inhalers Microfluidics - methods Models, Chemical Particle Size Pharmacology/Toxicology Pharmacy Research Article
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