Retrograde release of endocannabinoids inhibits presynaptic GABA release to second-order baroreceptive neurons in NTS

Abstract In prior studies, we found that activation of cannabinoid-1 receptors in the nucleus tractus solitarii (NTS) prolonged baroreflex-induced sympathoinhibition in rats. In many regions of the central nervous system, activation of cannabinoid-1 receptors presynaptically inhibits γ-aminobutyric...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Autonomic neuroscience 2010-12, Vol.158 (1), p.44-50
Hauptverfasser:	Chen, Chao-Yin, Bonham, Ann C, Dean, Caron, Hopp, Francis A, Hillard, Cecilia J, Seagard, Jeanne L
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Baroreflex Baroreflex - drug effects Baroreflex - physiology Biological and medical sciences Brainstem Cannabinoid Receptor Modulators - metabolism Cannabinoid Receptor Modulators - secretion Electrophysiology Endocannabinoids Excitatory Amino Acid Antagonists - pharmacology Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - metabolism gamma-Aminobutyric Acid - secretion Inhibitory Postsynaptic Potentials - drug effects Inhibitory Postsynaptic Potentials - physiology Male Medical Education Neural Inhibition - drug effects Neural Inhibition - physiology Neurons - drug effects Neurons - metabolism Neurons - secretion Peripheral nervous system. Autonomic nervous system. Neuromuscular transmission. Ganglionic transmission. Electric organ Presynaptic Terminals - drug effects Presynaptic Terminals - metabolism Presynaptic Terminals - secretion Rat Rats Rats, Sprague-Dawley Sodium Channel Blockers - pharmacology Solitary Nucleus - cytology Solitary Nucleus - drug effects Solitary Nucleus - physiology Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!