Purine nucleoside phosphorylase: A new marker for free oxygen radical injury to the endothelial cell

The effect of ischemia and reperfusion on purine nucleoside phosphorylase was studied in an isolated perfused rat liver model. This enzyme is localized primarily in the cytoplasm of the endothelial and Kupffer cells; some activity is associated with the parenchymal cells. Levels of this enzyme accur...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 1990-02, Vol.11 (2), p.193-198
Hauptverfasser: Rao, Prakash N., Walsh, Thomas R., Makowka, Leonard, Rubin, Randy S., Weber, Thomas, Snyder, James T., Starzl, Thomas E.
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Sprache:eng
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