Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model

Bacteria associated with the onset of type 1 diabetes in a rat model system were identified. In two experiments, stool samples were collected at three time points after birth from bio-breeding diabetes-prone (BB-DP) and bio-breeding diabetes-resistant (BB-DR) rats. DNA was isolated from these sample...

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Veröffentlicht in:	The ISME Journal 2009-05, Vol.3 (5), p.536-548
Hauptverfasser:	Roesch, Luiz FW, Lorca, Graciela L, Casella, George, Giongo, Adriana, Naranjo, Andres, Pionzio, Arianna M, Li, Nan, Mai, Volker, Wasserfall, Clive H, Schatz, Desmond, Atkinson, Mark A, Neu, Josef, Triplett, Eric W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria Bacteria - classification Bacteria - isolation & purification Bacteroides Bifidobacterium Biodiversity Biomedical and Life Sciences Cluster Analysis Deoxyribonucleic acid Diabetes Mellitus DNA DNA, Bacterial - chemistry DNA, Bacterial - genetics DNA, Ribosomal - chemistry DNA, Ribosomal - genetics DNA, Ribosomal Spacer - chemistry DNA, Ribosomal Spacer - genetics Ecology Evolutionary Biology Gastrointestinal Tract - microbiology Genes, rRNA Genotypes Lactobacillus Life Sciences Microbial Ecology Microbial Genetics and Genomics Microbiology Molecular Sequence Data original-article Phylogeny Rats RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics Sequence Analysis, DNA Sequence Homology, Nucleic Acid
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