Immunological and biological properties of iodoinsulin labeled with one or less atoms of iodine per molecule

Experiments were designed to compare the distribution of free and antibody-bound unlabeled insulin to the distribution of free and antibody-bound insulin-(125)I. The insulin antibody was incorporated in a specific immune precipitate similar to the one used by Hales and Randle for the radioimmune ass...

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Veröffentlicht in:	J. Clin. Invest., 47: 474-87(Mar. 1968) 47: 474-87(Mar. 1968), 1968-03, Vol.47 (3), p.474-487
Hauptverfasser:	Arquilla, E R, Ooms, H, Mercola, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Animals ANTIBODIES ANTIBODIES/reactions with insulin, effects of iodine-125 labeling on Antigen-Antibody Reactions ANTIGENS Electrophoresis GAMMA RADIATION Gels Guinea Pigs Hemolysis HORMONES HORMONES, PANCREATIC/insulin, antibody-combining properties of, effects of iodine-125 incorporation on Immune Sera INSULIN Insulin - analysis Insulin - pharmacology Insulin Antibodies Iodine - analysis IODINE 125 Iodine Isotopes IODINE ISOTOPES I-125/use of insulin incorporated, for study of attenuation of antibody-combining properties Iodoproteins LABELLED COMPOUNDS N28140 -Life Sciences-Radiation Effects on Biochemicals Protein Binding Rabbits RADIATION EFFECTS Radioimmunoassay
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