Renal vasoconstriction caused by short-term cholesterol feeding is corrected by thromboxane antagonist or probucol

Recent studies indicate that short-term cholesterol feeding causes vascular hyperreactivity and/or increased tone in certain vascular beds. The present study in rats examined the effect of 3 wk of cholesterol-supplemented diet (CSD) on renal hemodynamics. We tested the hypothesis that LDL oxidized i...

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Veröffentlicht in:	The Journal of clinical investigation 1990-11, Vol.86 (5), p.1707-1714
Hauptverfasser:	KAPLAN, R, AYNEDJIAN, H. S, SCHLONDORFF, D, BANK, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cholesterol, Dietary - administration & dosage Dinoprostone - analysis Dinoprostone - urine Fundamental and applied biological sciences. Psychology Glomerular Filtration Rate Kidney - blood supply Lipoproteins, LDL - administration & dosage Male Oxidation-Reduction Phenylacetates - pharmacology Probucol - pharmacology Rats Rats, Inbred Strains Receptors, Prostaglandin - antagonists & inhibitors Receptors, Thromboxane Renal Circulation Saralasin - pharmacology Sulfonamides - pharmacology Thromboxane B2 - analysis Thromboxane B2 - urine Vasoconstriction Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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