Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension

BACKGROUND: Essential hypertension is characterized by reciprocal relations between endothelial dysfunction and insulin resistance. Cocoa flavanols stimulate production of the vasodilator nitric oxide from vascular endothelium. OBJECTIVE: The objective was to test the hypothesis that consumption of...

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Veröffentlicht in:	The American journal of clinical nutrition 2008-12, Vol.88 (6), p.1685-1696
Hauptverfasser:	Muniyappa, Ranganath, Hall, Gail, Kolodziej, Terrie L, Karne, Rajaram J, Crandon, Sonja K, Quon, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult adults Aged Beverages Biological and medical sciences Blood pressure Brachial Artery Cacao - chemistry Chromatography, High Pressure Liquid Clinical trials Cocoa cocoa (beverage) Cross-Over Studies dietary nutrient sources Double-Blind Method Drug resistance endothelial cells Endothelium, Vascular - drug effects essential hypertension experimental diets Feeding. Feeding behavior Female flavanols Flavonols - blood Flavonols - pharmacokinetics Flavonols - pharmacology Fundamental and applied biological sciences. Psychology Glucose Clamp Technique Humans Hypertension Hypertension - blood Hypertension - drug therapy Insulin Insulin - metabolism Insulin Resistance Male Middle Aged Regional Blood Flow Treatment Outcome vasodilation Vertebrates: anatomy and physiology, studies on body, several organs or systems Young Adult
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