Endothelial cell migration during murine yolk sac vascular remodeling occurs via a Rac1 and FAK activation pathway in vivo

The molecular mechanism(s) controlling cell migration during vascular morphogenesis in vivo remain largely undefined. To address this within a physiological context, we employed retinaldehyde dehydrogenase-2 ( Raldh 2) null mouse embryos and demonstrate that retinoic acid (RA) deficiency results in...

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Veröffentlicht in:Developmental dynamics 2010-10, Vol.239 (10), p.2570-2583
Hauptverfasser: Enciso, Josephine M., Konecny, Christine M., Karpen, Heidi E., Hirschi, Karen K.
Format: Artikel
Sprache:eng
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