Beta-adrenergic stimulation of adenine nucleotide catabolism and purine release in human adipocytes

The effects of beta-adrenergic agonists on ATP utilization and adenine nucleotide breakdown in human adipocytes were examined. The catecholamine-induced increase in cAMP was associated with an enhancement of adenine nucleotide catabolism resulting in an increase in release of inosine and hypoxanthin...

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Veröffentlicht in:	The Journal of clinical investigation 1990, Vol.85 (1), p.106-114
1. Verfasser:	KATHER, H
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-3-isobutylxanthine - pharmacology 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone - pharmacology adenine nucleotides Adenine Nucleotides - metabolism Adenosine - pharmacology Adenosine Triphosphate - metabolism adipocytes Adipose Tissue - drug effects Adipose Tissue - metabolism Biological and medical sciences Cell metabolism, cell oxidation Cell physiology Cells, Cultured Cyclic AMP - metabolism Female Fundamental and applied biological sciences. Psychology Humans Hypoxanthine Hypoxanthines - pharmacology Inosine - pharmacology Isoproterenol - pharmacology Kinetics Lipolysis - drug effects Molecular and cellular biology Propranolol - pharmacology Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - physiology
Online-Zugang:	Volltext
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